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In recent years, increasing insights into virus–host interactions have revealed that the successful replication of the influenza virus depends not only on its genomic structure but also on its precise manipulation of host cellular physiology [7,8]

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1 Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, OR, 2 Department of Immunology, Janssen Scientific Affairs, LLC, Horsham, PA, 3 Department of Immunology, Janssen Research and Development, LLC, Spring House, PA, 4 Department of Immunology, University of Pennsylvania, Philadelphia, PA, 5 Department of Biostatistics, Janssen Research and Development, LLC, Spring House, PA, 6 Department of Rheumatology and Clinical Immunogenetics, University of Texas McGovern Medical School, Houston, TX, United States